The Covid-19 pandemic has challenged many companies’ operational models, and will accelerate a global trend towards supply-chain resiliency and operational efficiency. Key to both will be a massive increase in gathering and analyzing operational data, and acting quickly and decisively on the insights gained. Successful operations in the coming years will, then, be more Connected, Automated, and increasingly Resilient in the face of disruptions. MIT and the MIT-connected startup community have been innovating in supply chains and operational efficiency for many years, and we have commercial, industry-ready solutions that will be key to this transformation. This workshop will present perspectives from industry leaders, academics, and corporate investors, while showcasing several MIT-connected startups in this field.