Co-investigators Jongyoon Han , Jacob White
The goat of this project is to use radically improved modeling and optimization methodologies to streamline the design of microfluidic systems and the micro- and nano-elements within. The strategy Is to dramatically expand the range of problems that can be efficiently modeled. such that realistic multi-domain physical models can be used to design the systems, through the combination of advanced computation and well-controlled experimental research. Methodologies will be developed to efficiently simulate a range of physical interaction among biomolecules, device structures and fluids, which are critical to manipulating cells and biomolecules in micro-/nano-fluidic systems. These methodologies will be realized as software for modeling multi-domain physics and to then develop actual devices.